Over the years, medical science has been continuously evolving to accommodate any changes in the medical landscape. It does not cease from looking for solutions and treatments of various diseases. The discovery of liposome is among the most remarkable breakthroughs in the industry. This is used to aid drug intake to enhance its efficiency, increase success rate in organ transplant surgery and treat several medical malfunctions.
Liposomes are microscopical vesicles developed in an artificial environment like a laboratory. These are composed of phospholipids that are naturally produced or extracted from another source. Its outer wall has similar composition to that of a cell wall. This allows direct interaction between the cells and the liposomes. These tiny, spheroid-shaped bubbles are typically watery in its core.
The most common use of this structure is to introduce medicines to the patient's body more effectively. The unique property of the vesicles allow drugs to be delivered in specific parts of the body through diffusion. With its double-layered membranes, the vesicle can carry hydrophobic drugs. This can also be used to carry biological agents like antibodies to targeted parts in the patient's body.
The spheroid bubbles can also extend the delivery time for the drugs while keeping its potency. The bi-layered bubble slowly releases the drugs over a span of time. Thus, side-effects may be reduced. Since the vesicle only releases the medication to the affected tissues, it can also help maximize the effects of the drugs.
The structure is considered a natural treatment to cancer, too. The vesicle has the ability to target cancer cells. It can also slip right into the tumor by following the blood flow. Liposomes are small in size, so it does not stray away from the bloodstream. Not to mention its composition that is closely similar to blood vessels, which are trapped inside the endothelial wall. In contrast, cancer cells are leaky in nature. It lets through even the small particles to escape.
The vesicles can help neutralize autoimmune reactions of the body. Rejections occur in many transplant surgeries when the body identifies the transplanted organ as foreign. The immune system's natural reaction would be to attack the entity in order to protect the body from infestation. The use of artificial lipid can suppress the progress of immune system, so the body has enough time to accommodate the newly introduced organ.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
These vesicles come in various sizes. The vessels are typically small for the white blood cells to easily engulf the bubbles before the drug it carries can be released. Prior to its production, the size and numbers of vesicles to be created have to be determined. Possibilities of reproduction must also be anticipated.
One reservation for medical practitioners regarding this extremely useful breakthrough is its production costs. Mass production is currently unavailable since the vessels cannot last long after its creation. There has been cases of instability and unintentional mixture of drugs as well. Other than that, liposome is definitely a promising discovery.
Liposomes are microscopical vesicles developed in an artificial environment like a laboratory. These are composed of phospholipids that are naturally produced or extracted from another source. Its outer wall has similar composition to that of a cell wall. This allows direct interaction between the cells and the liposomes. These tiny, spheroid-shaped bubbles are typically watery in its core.
The most common use of this structure is to introduce medicines to the patient's body more effectively. The unique property of the vesicles allow drugs to be delivered in specific parts of the body through diffusion. With its double-layered membranes, the vesicle can carry hydrophobic drugs. This can also be used to carry biological agents like antibodies to targeted parts in the patient's body.
The spheroid bubbles can also extend the delivery time for the drugs while keeping its potency. The bi-layered bubble slowly releases the drugs over a span of time. Thus, side-effects may be reduced. Since the vesicle only releases the medication to the affected tissues, it can also help maximize the effects of the drugs.
The structure is considered a natural treatment to cancer, too. The vesicle has the ability to target cancer cells. It can also slip right into the tumor by following the blood flow. Liposomes are small in size, so it does not stray away from the bloodstream. Not to mention its composition that is closely similar to blood vessels, which are trapped inside the endothelial wall. In contrast, cancer cells are leaky in nature. It lets through even the small particles to escape.
The vesicles can help neutralize autoimmune reactions of the body. Rejections occur in many transplant surgeries when the body identifies the transplanted organ as foreign. The immune system's natural reaction would be to attack the entity in order to protect the body from infestation. The use of artificial lipid can suppress the progress of immune system, so the body has enough time to accommodate the newly introduced organ.
The vesicles are not spontaneously produced, though. There are various methods used to create these drug vessels according to its function and purpose. Its method of dissemination must be considered as well as the type of materials that will be transported.
These vesicles come in various sizes. The vessels are typically small for the white blood cells to easily engulf the bubbles before the drug it carries can be released. Prior to its production, the size and numbers of vesicles to be created have to be determined. Possibilities of reproduction must also be anticipated.
One reservation for medical practitioners regarding this extremely useful breakthrough is its production costs. Mass production is currently unavailable since the vessels cannot last long after its creation. There has been cases of instability and unintentional mixture of drugs as well. Other than that, liposome is definitely a promising discovery.
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